What is meant by “The Liver’s Waste Disposal Role”?

The Liver's ("Liver") waste disposal role is of utmost importance to good health. When it begins to fail as a blood filter, we may expect that toxic material will enter the general circulation. It is this toxic material in the general circulation which stimulates the endocrine (in-pouring) to over-activity in a valiant attempt to help the body neutralize and eliminate the irritants resulting from improper digestion ("The art and importance of Correct Chewing") of proteins, sugars, starches and fats.